Oral Solution Medicine Enrofloxacin 10% Colistin Sulphate 0.5% Oral Liquid
The combination of colistin and enrofloxacin acts additive. Enrofloxacin is a synthetic, broad spectrum antimicrobial substance, belonging to the fluoroquinoline group of antibiotics, Enrofloxacin is active against Gram-negative and Gram-positive bacteria and mycoplasmas. It is well absorbed after oral administration and rapidly excreted in the bile and urine, mostly as enrofloxacin and the metabolitw ciprofloxacin. Colistin is an antibiotic from the group of polymyxins with bactericidal action and Salmonella spp. It is absorbed poorly after oral administration and serum concentrationa are generally undetectable in target species. Orally administered are generally undetectable in target species. Orally administered colistin is eliminated almost totally in faeces.
Enrofloxacin + Colistin Oral Solution is indicated for gastrointestinal, respiratory and urinary tract infections caused by colistin and enrofloxacin sensitive micro-organisms like Campylobacter, E.coli, Haemophilus, Mycoplasm, Pasteurella and Salmonella spp. In poultry and swine.
Cases of hypersensitivity to colistin and/or enorfloxacin or to any of the excipients.
Administration to animals with seriously impaired renal and/or hepatic functions.
Cases of resistance against quinolones and/or colistin.
Administration to poultry producting eggs for human consumption or in pregnant or lactating animals.
Administration of Enrofloxacin + Colistin Oral Solution in subtherapeutic doses or for prevention.
All members of the quinolone family of antibiotic have the ability to cause articular lesions in young animals.
Digestive alterations may appear, such as intestinal dysbiosis, accumulation of gases, mild diarrhea or vomiting.
Side-effects or quinolones like rash and central nervous system disturbance may occur.
During a period of rapid growth, enrofloxacin may affect joint cartilage.
DOSAGE AND ADMINISTRATION:
For oral administration with drinking water:
Poultry: 1 litre per 2000 liters of drinking water for 3-5days.
Pigs: 1 litre per 2000 liter of drinking water for 3-5 days.
Only sufficient medicated drinking water should be prepared to cover daily requirement. Medicated drinking water should be replaced every 24 hours.
For meat and offal: 9 days.
Keep out of reach of children.
For animal treatment only